Ethosomes Loaded with Cryptotanshinone for Acne Treatment through Topical Gel Formulation

Ethosomes Loaded with Cryptotanshinone for Acne Treatment through Topical Gel Formulation

The aim of this study was to develop ethosomes loaded with cryptotanshinone (CPT) and formulate them as a topical gel for the treatment of acne. Ethosomes were prepared and evaluated for vesicle size, CPT loading and encapsulation efficiency. Optimized ethosomes were formulated as Carbomer 974 gels and compared with conventional hydroethanolic gels for transdermal permeation and skin deposition...

Formulation and quality control of a topical gel product for treatment of melasmaFormulation and quality control of a topical gel product for treatment of melasma

Background and objectives: Melasma is one of the most common pigmentary disorders. It has a considerable impact on quality of life. The treatment of melasma has still remained a challenge because the efficient treatment has not been proven until now and there is still a need to find new depigmenting products.Allium cepa L. and Cucumis melo L. seeds as well as ...

Formulation of tretinoin-loaded topical proniosomes for treatment of acne: in-vitro characterization, skin irritation test and comparative clinical study.

Tretinoin (TRT) is a widely used retinoid for the topical treatment of acne, photo-aged skin, psoriasis and skin cancer which makes it a good candidate for topical formulation. Yet side effects, like redness, swelling, peeling, blistering and, erythema, in addition to its high lipophilicity make this challenging. Therefore, the aim of this study was the development of TRT-loaded proniosomes to ...

New Topical Acne Treatment

In vitro and in vivo assessment of polyherbal topical gel formulation for the treatment of acne vulgaris

Anti-acne herbal formulations are used for the treatment of acne vulgaris with the added advantage of not producing adverse effects unlike synthetic drugs. Phytoconstituents present in methanolic extracts of Camellia sinensis (CSME), Glycyrrhiza glabra (GGME) and Calendula officinalis (COME) have antibacterial and antioxidant properties. Validated HPTLC fingerprinting confirmed the presence of ...